Melanocyte Activation Mechanisms and Rational Therapeutic Treatments of Solar Lentigos

Melanocyte Activation Mechanisms and Rational Therapeutic Treatments of Solar Lentigos

To characterize the pathobiology of solar lentigos (SLs), analyses by semiquantitative RT-PCR, Western blotting, and immunohistochemistry revealed the upregulated expression of endothelin (EDN)-1/endothelin B receptors (EDNBRs), stem cell factor (SCF)/c-KIT, and tumor necrosis factor (TNF)α...

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Bibliographic Details
Main Author: Genji Imokawa
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
solar lentigo
endothelin
stem cell factor
keratinocyte growth factor
interleukin-1
tumor necrosis factor α
intracellular signaling
calcium mobilization
signaling blocker
<i>M. chamomilla</i>
ascorbate-phosphate Na
whitening agent
tyrosinase inhibitor
Online Access:https://www.mdpi.com/1422-0067/20/15/3666

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https://www.mdpi.com/1422-0067/20/15/3666

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