Moisture-Resistant Co-Spray-Dried Netilmicin with <span style="font-variant: small-caps">l</span>-Leucine as Dry Powder Inhalation for the Treatment of Respiratory Infections

Moisture-Resistant Co-Spray-Dried Netilmicin with <span style="font-variant: small-caps">l</span>-Leucine as Dry Powder Inhalation for the Treatment of Respiratory Infections

Netilmicin (NTM) is one of the first-line drugs for lower respiratory tract infections (LRTI) therapy, but its nephrotoxicity and ototoxicity caused by intravenous injection restrict its clinical application. Dry powder inhalation (DPI) is a popular local drug delivery system that is introduced as a...

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Bibliographic Details
Main Authors: Yingtong Cui, Xuejuan Zhang, Wen Wang, Zhengwei Huang, Ziyu Zhao, Guanlin Wang, Shihao Cai, Hui Jing, Ying Huang, Xin Pan, Chuanbin Wu
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Pharmaceutics
Subjects:
dry powder inhalation
<span style="font-variant: small-caps">l</span>-leucine
netilmicin
moisture resistant
lower respiratory tract infection
Online Access:https://www.mdpi.com/1999-4923/10/4/252

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https://www.mdpi.com/1999-4923/10/4/252

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