microRNA-mediated regulation of microRNA machinery controls cell fate decisions
microRNAs associate with Argonaute proteins, forming the microRNA-induced silencing complex (miRISC), to repress target gene expression post-transcriptionally. Although microRNAs are critical regulators in mammalian cell differentiation, our understanding of how microRNA machinery, such as the miRIS...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-10-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/72289 |