Multiple Poliovirus Proteins Repress Cytoplasmic RNA Granules

We have previously shown that poliovirus (PV) infection induces stress granule (SG) formation early in infection and then inhibits the formation of SG and disperses processing bodies (PBs) by the mid-phase of infection. Loss of SG was linked to cleavage of G3BP1 by viral 3C proteinase (3Cpro), howev...

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Bibliographic Details
Main Authors: Jonathan D. Dougherty, Wei-Chih Tsai, Richard E. Lloyd
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/7/12/2922