Cell softening in malignant progression of human lung cancer cells by activation of receptor tyrosine kinase AXL

Cell softening in malignant progression of human lung cancer cells by activation of receptor tyrosine kinase AXL

Abstract To study the role of cell softening in malignant progression, Transwell assay and atomic force microscope were used to classify six human non-small cell lung cancer cell lines into two groups: a high motility-low stiffness (HMLS) group and a low motility-high stiffness (LMHS) group. We foun...

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Bibliographic Details
Main Authors: Keisuke Iida, Ryo Sakai, Shota Yokoyama, Naritaka Kobayashi, Shodai Togo, Hiroshi Y. Yoshikawa, Anchalee Rawangkan, Kozue Namiki, Masami Suganuma
Format: Article
Language:English
Published: Nature Publishing Group 2017-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-18120-4

Internet

https://doi.org/10.1038/s41598-017-18120-4

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