Internalization of the Extracellular Full-Length Tau Inside Neuro2A and Cortical Cells Is Enhanced by Phosphorylation

Tau protein is mainly intracellular. However, several studies have demonstrated that full-length Tau can be released into the interstitial fluid of the brain. The physiological or pathological function of this extracellular Tau remains unknown. Moreover, as evidence suggests, extracellular Tau aggre...

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Bibliographic Details
Main Authors: Mathilde Wauters, Ruddy Wattiez, Laurence Ris
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Biomolecules
Subjects:
Tau
Online Access:http://www.mdpi.com/2218-273X/6/3/36