An efficient strategy to induce and maintain in vitro human T cells specific for autologous non-small cell lung carcinoma.

BACKGROUND: The efficient expansion in vitro of cytolytic CD8+ T cells (CTLs) specific for autologous tumors is crucial both for basic and translational aspects of tumor immunology. We investigated strategies to generate CTLs specific for autologous Non-Small Cell Lung Carcinoma (NSCLC), the most fr...

Full description

Bibliographic Details
Main Authors: Glenda Canderan, Paola Gruarin, Daniela Montagna, Raffaella Fontana, Gabriele Campi, Giulio Melloni, Catia Traversari, Paolo Dellabona, Giulia Casorati
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2918513?pdf=render