Somatic Mutations of <i>lats2</i> Cause Peripheral Nerve Sheath Tumors in Zebrafish

The cellular signaling pathways underlying peripheral nerve sheath tumor (PNST) formation are poorly understood. Hippo signaling has been recently implicated in the biology of various cancers, and is thought to function downstream of mutations in the known PNST driver, <i>NF2</i>. Utiliz...

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Bibliographic Details
Main Authors: Zachary J. Brandt, Paula N. North, Brian A. Link
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
Yap
Taz
Online Access:https://www.mdpi.com/2073-4409/8/9/972