ATXN7L3 positively regulates SMAD7 transcription in hepatocellular carcinoma with growth inhibitory function

ATXN7L3 positively regulates SMAD7 transcription in hepatocellular carcinoma with growth inhibitory function

Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer death worldwide, with unmet need for the pharmacological therapy. The functions of ATXN7L3 in HCC progression are not known. Methods: RNA sequence, quantitative real-time PCR, and western blot were performed to detect gene expre...

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Bibliographic Details
Main Authors: Ning Sun, Xinping Zhong, Shengli Wang, Kai Zeng, Hongmiao Sun, Ge Sun, Renlong Zou, Wei Liu, Wensu Liu, Lin Lin, Huijuan Song, Chi Lv, Chunyu Wang, Yue Zhao
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:EBioMedicine
Subjects:
ATXN7L3
Estrogen receptor α
Co-regulator
Deubiquitination modification
Hepatocellular carcinoma
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420304849

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http://www.sciencedirect.com/science/article/pii/S2352396420304849

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