Hippocampal and Hippocampal-Subfield Volumes From Early-Onset Major Depression and Bipolar Disorder to Cognitive Decline

Hippocampal and Hippocampal-Subfield Volumes From Early-Onset Major Depression and Bipolar Disorder to Cognitive Decline

Background: The hippocampus and its subfields (HippSub) are reported to be diminished in patients with Alzheimer's disease (AD), bipolar disorder (BD), and major depressive disorder (MDD). We examined these groups vs healthy controls (HC) to reveal HippSub alterations between diseases.Methods:...

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Main Authors: Niels Hansen, Aditya Singh, Claudia Bartels, Frederic Brosseron, Katharina Buerger, Arda C. Cetindag, Laura Dobisch, Peter Dechent, Birgit B. Ertl-Wagner, Klaus Fliessbach, John D. Haynes, Michael T. Heneka, Daniel Janowitz, Ingo Kilimann, Christoph Laske, Coraline D. Metzger, Matthias H. Munk, Oliver Peters, Josef Priller, Nina Roy, Klaus Scheffler, Anja Schneider, Annika Spottke, Eike J. Spruth, Stefan Teipel, Maike Tscheuschler, Ruth Vukovich, Jens Wiltfang, Emrah Duezel, Frank Jessen, Roberto Goya-Maldonado
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer's disease
cognitive impairment
early-onset depression
hippocampus
hippocampal subfields
MRI volumetry
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.626974/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2021.626974/full

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