The effect of an interleukin receptor antagonist (IL-1ra) on colonocyte eicosanoid release

We investigated whether an interleukin 1 receptor antagonist (IL-1ra) altered cellular release of prostanoids and leukotrienes in a transformed colonic cell line (CACO-2) in the presence of proinflammatory stimuli. Cellular inflammation was induced by treatment with lipopolysaccharide (LPS) or the c...

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Bibliographic Details
Main Authors: G. S. Smith, C. Rieckenberg, W. E. Longo, D. L. Kaminski, J. E. Mazuski, Y. Deshpande, T. A. Miller
Format: Article
Language:English
Published: Hindawi Limited 1996-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/S0962935196000622