Induction of Bcl-2 expression by hepatitis B virus pre-S2 mutant large surface protein resistance to 5-fluorouracil treatment in Huh-7 cells.

Induction of Bcl-2 expression by hepatitis B virus pre-S2 mutant large surface protein resistance to 5-fluorouracil treatment in Huh-7 cells.

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide with poor prognosis due to resistance to conventional chemotherapy and limited efficacy of radiotherapy. Our previous studies have indicated that expression of Hepatitis B virus pre-S2 large mutant surface an...

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Bibliographic Details
Main Authors: Jui-Hsiang Hung, Yen-Ni Teng, Lily Hui-Ching Wang, Ih-Jen Su, Clay C C Wang, Wenya Huang, Kuan-Han Lee, Kuan-Ying Lu, Lyu-Han Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3245229?pdf=render

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http://europepmc.org/articles/PMC3245229?pdf=render

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