A Metagenomics Study on Hirschsprung's Disease Associated Enterocolitis: Biodiversity and Gut Microbial Homeostasis Depend on Resection Length and Patient's Clinical History

A Metagenomics Study on Hirschsprung's Disease Associated Enterocolitis: Biodiversity and Gut Microbial Homeostasis Depend on Resection Length and Patient's Clinical History

Objectives: Since 2010, several researches demonstrated that microbiota dynamics correlate and can even predispose to Hirschsprung (HSCR) associated enterocolitis (HAEC). This study aims at assessing the structure of the microbiota of HSCR patients in relation to extent of aganglionosis and HAEC sta...

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Bibliographic Details
Main Authors: Alessio Pini Prato, Casey Bartow-McKenney, Kelly Hudspeth, Manuela Mosconi, Valentina Rossi, Stefano Avanzini, Maria G. Faticato, Isabella Ceccherini, Francesca Lantieri, Girolamo Mattioli, Denise Larson, William Pavan, Carlotta De Filippo, Monica Di Paola, Domenico Mavilio, Duccio Cavalieri
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Pediatrics
Subjects:
metagenomics
enterocolitis
Hirschsprung
RET gene
aganglionosis
Online Access:https://www.frontiersin.org/article/10.3389/fped.2019.00326/full

Internet

https://www.frontiersin.org/article/10.3389/fped.2019.00326/full

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