Loss of Tumor Suppressor Gene Function in Human Cancer: An Overview

Cancer is a disease caused by the accumulation of genetic and epigenetic changes in two types of genes: tumor suppressor genes (TSGs) and proto-oncogenes. Extensive research has been conducted over the last few decades to elucidate the role of TSGs in cancer development. In cancer, loss of TSG funct...

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Bibliographic Details
Main Authors: Li-Hui Wang, Chun-Fu Wu, Nirmal Rajasekaran, Young Kee  Shin
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:https://www.karger.com/Article/FullText/495956