Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice

Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice

Munc13 isoforms are constituents of the presynaptic compartment of chemical synapses, where they govern important steps in preparing synaptic vesicles for exocytosis. The role of Munc13-1, -2 and -3 is well documented in brain neurons, but less is known about their function and distribution among th...

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Bibliographic Details
Main Authors: Kaspar Gierke, Julia von Wittgenstein, Maike Hemmerlein, Jenny Atorf, Anneka Joachimsthaler, Jan Kremers, Benjamin H. Cooper, Frederique Varoqueaux, Hanna Regus-Leidig, Johann Helmut Brandstätter
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
Munc13-1
ubMunc13-2
brMunc13-2
Munc13-3
ribbon synapse
conventional synapse
Online Access:https://www.mdpi.com/1422-0067/21/21/7848

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https://www.mdpi.com/1422-0067/21/21/7848

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