Genomic epidemiology of artemisinin resistant malaria

The current epidemic of artemisinin resistant Plasmodium falciparum in Southeast Asia is the result of a soft selective sweep involving at least 20 independent kelch13 mutations. In a large global survey, we find that kelch13 mutations which cause resistance in Southeast Asia are present at low freq...

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Bibliographic Details
Main Author: MalariaGEN Plasmodium falciparum Community Project
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/08714