Glutaredoxin-1 overexpression enhances neovascularization and diminishes ventricular remodeling in chronic myocardial infarction.

Glutaredoxin-1 overexpression enhances neovascularization and diminishes ventricular remodeling in chronic myocardial infarction.

Oxidative stress plays a critical role in the pathophysiology of cardiac failure, including the modulation of neovascularization following myocardial infarction (MI). Redox molecules thioredoxin (Trx) and glutaredoxin (Grx) superfamilies actively maintain intracellular thiol-redox homeostasis by sca...

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Main Authors: Ram Sudheer Adluri, Mahesh Thirunavukkarasu, Lijun Zhan, Nageswara Rao Dunna, Yuzo Akita, Vaithinathan Selvaraju, Hajime Otani, Juan A Sanchez, Ye-Shih Ho, Nilanjana Maulik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3327713?pdf=render

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http://europepmc.org/articles/PMC3327713?pdf=render

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