Pan-cancer analysis of m5C regulator genes reveals consistent epigenetic landscape changes in multiple cancers

Abstract Background 5-Methylcytosine (m5C) is a reversible modification to both DNA and various cellular RNAs. However, its roles in developing human cancers are poorly understood, including the effects of mutant m5C regulators and the outcomes of modified nucleobases in RNAs. Methods Based on The C...

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Bibliographic Details
Main Authors: Yuting He, Xiao Yu, Menggang Zhang, Wenzhi Guo
Format: Article
Language:English
Published: BMC 2021-07-01
Series:World Journal of Surgical Oncology
Subjects:
Online Access:https://doi.org/10.1186/s12957-021-02342-y