Mimicking of Phase I Metabolism Reactions of Molindone by HLM and Photocatalytic Methods with the Use of UHPLC-MS/MS

Establishing the metabolism pathway of the drug undergoing the hepatic biotransformation pathway is one of the most important aspects in the preclinical discovery process since the presence of toxic or reactive metabolites may result in drug withdrawal from the market. In this study, we present the...

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Bibliographic Details
Main Authors: Maciej Gawlik, Vladimir Savic, Milos Jovanovic, Robert Skibiński
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Molecules
Subjects:
hlm
Online Access:https://www.mdpi.com/1420-3049/25/6/1367