Chemically Programmed Vaccines: Iron Catalysis in Nanoparticles Enhances Combination Immunotherapy and Immunotherapy-Promoted Tumor Ferroptosis

Chemically Programmed Vaccines: Iron Catalysis in Nanoparticles Enhances Combination Immunotherapy and Immunotherapy-Promoted Tumor Ferroptosis

Summary: Immunotherapy has yielded impressive results, but only for a minority of patients with cancer. Therefore, new approaches that potentiate immunotherapy are a pressing medical need. Ferroptosis is a newly described type of programmed cell death driven by iron-dependent phospholipid peroxidati...

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Bibliographic Details
Main Authors: Ane Ruiz-de-Angulo, Marc Bilbao-Asensio, James Cronin, Stephen J. Evans, Martin J.D. Clift, Jordi Llop, Irene V.J. Feiner, Rhiannon Beadman, Kepa Zamacola Bascarán, Juan C. Mareque-Rivas
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:iScience
Subjects:
Immunology
Biomaterials
Nanomaterials
Cancer
Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422030691X

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http://www.sciencedirect.com/science/article/pii/S258900422030691X

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