Phosphorylation of TXNIP by AKT Mediates Acute Influx of Glucose in Response to Insulin

Phosphorylation of TXNIP by AKT Mediates Acute Influx of Glucose in Response to Insulin

Growth factors, such as insulin, can induce both acute and long-term glucose uptake into cells. Apart from the rapid, insulin-induced fusion of glucose transporter (GLUT)4 storage vesicles with the cell surface that occurs in muscle and adipose tissues, the mechanism behind acute induction has been...

Full description

Bibliographic Details
Main Authors: Althea N. Waldhart, Holly Dykstra, Anderson S. Peck, Elissa A. Boguslawski, Zachary B. Madaj, Jennifer Wen, Kelsey Veldkamp, Matthew Hollowell, Bin Zheng, Lewis C. Cantley, Timothy E. McGraw, Ning Wu
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Cell Reports
Subjects:
GLUT4
TXNIP
insulin
AKT
glucose
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717306836

Internet

http://www.sciencedirect.com/science/article/pii/S2211124717306836

Similar Items