Integration of population and functional genomics to understand mechanisms of artemisinin resistance in Plasmodium falciparum

Integration of population and functional genomics to understand mechanisms of artemisinin resistance in Plasmodium falciparum

Resistance to antimalarial drugs, and in particular to the artemisinin derivatives and their partner drugs, threatens recent progress toward regional malaria elimination and eventual global malaria eradication. Population-level studies utilizing whole-genome sequencing approaches have facilitated th...

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Bibliographic Details
Main Authors: Jenna Oberstaller, Linda Zoungrana, Carl D. Bannerman, Samira Jahangiri, Ankit Dwivedi, Joana C. Silva, John H. Adams, Shannon Takala-Harrison
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
P. falciparum
Drug resistance
iSAFE
Functional genomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320721000257

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http://www.sciencedirect.com/science/article/pii/S2211320721000257

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