Lipoprotein lipase activity and interactions studied in human plasma by isothermal titration calorimetry

LPL hydrolyzes triglycerides in plasma lipoproteins. Due to the complex regulation mechanism, it has been difficult to mimic the physiological conditions under which LPL acts in vitro. We demonstrate that isothermal titration calorimetry (ITC), using human plasma as substrate, overcomes several limi...

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Bibliographic Details
Main Authors: Mart Reimund, Oleg Kovrov, Gunilla Olivecrona, Aivar Lookene
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520314553