Opposite Regulatory Effects of Immobilized Cations on the Folding Vs. Assembly of Melittin

Ions are crucial in modulating the protein structure. For the free ions in bulk solution, ammonium is kosmotropic (structure forming) and guanidinium is chaotropic (structure breaking) to the protein structure within the Hofmeister series. However, the effect of immobilized ions on a protein surface...

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Bibliographic Details
Main Authors: Lanlan Yu, Zhun Deng, Wenbo Zhang, Shuli Liu, Feiyi Zhang, Jianjian Zhou, Chunhua Ma, Chenxuan Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.685947/full