ZFN-Site searches genomes for zinc finger nuclease target sites and off-target sites

<p>Abstract</p> <p>Background</p> <p>Zinc Finger Nucleases (ZFNs) are man-made restriction enzymes useful for manipulating genomes by cleaving target DNA sequences. ZFNs allow therapeutic gene correction or creation of genetically modified model organisms. ZFN specifici...

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Bibliographic Details
Main Authors: Iseli Christian, Ambrosini Giovanna, Cradick Thomas J, Bucher Philipp, McCaffrey Anton P
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/152