Liver-on-a-Chip‒Magnetic Nanoparticle Bound Synthetic Metalloporphyrin-Catalyzed Biomimetic Oxidation of a Drug in a Magnechip Reactor

Liver-on-a-Chip‒Magnetic Nanoparticle Bound Synthetic Metalloporphyrin-Catalyzed Biomimetic Oxidation of a Drug in a Magnechip Reactor

Biomimetic oxidation of drugs catalyzed by metalloporphyrins can be a novel and promising way for the effective and sustainable synthesis of drug metabolites. The immobilization of 5,10,15,20-tetrakis(2,3,4,5,6-pentafluorophenyl)iron(II) porphyrin (FeTPFP) and 5,10,15,20-tetrakis-(4-sulfonatophenyl)...

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Bibliographic Details
Main Authors: Balázs Decsi, Réka Krammer, Kristóf Hegedűs, Ferenc Ender, Benjámin Gyarmati, András Szilágyi, Róbert Tőtős, Gabriel Katona, Csaba Paizs, György T. Balogh, László Poppe, Diána Balogh-Weiser
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Micromachines
Subjects:
drug metabolism
biomimetic oxidation
microfluidics
organ-on-a-chip
liver-on-a-chip
Online Access:https://www.mdpi.com/2072-666X/10/10/668

Internet

https://www.mdpi.com/2072-666X/10/10/668

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