Loss of Leptin-Induced Modulation of Hippocampal Synaptic Trasmission and Signal Transduction in High-Fat Diet-Fed Mice

Loss of Leptin-Induced Modulation of Hippocampal Synaptic Trasmission and Signal Transduction in High-Fat Diet-Fed Mice

Hippocampal plasticity is triggered by a variety of stimuli including sensory inputs, neurotrophins and inflammation. Leptin, whose primary function is to regulate food intake and energy expenditure, has been recently shown to affect hippocampal neurogenesis and plasticity. Interestingly, mice fed a...

Full description

Bibliographic Details
Main Authors: Marco Mainardi, Matteo Spinelli, Federico Scala, Andrea Mattera, Salvatore Fusco, Marcello D’Ascenzo, Claudio Grassi
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
patch-clamp
STAT-3
SOCS-3
ObR
CA1
Schaffer collateral
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00225/full

Internet

http://journal.frontiersin.org/article/10.3389/fncel.2017.00225/full

Similar Items