The Sigma-2 Receptor and Progesterone Receptor Membrane Component 1 are Different Binding Sites Derived From Independent Genes

The sigma-2 receptor (S2R) is a potential therapeutic target for cancer and neuronal diseases. However, the identity of the S2R has remained a matter of debate. Historically, the S2R has been defined as (1) a binding site with high affinity to 1,3-di-o-tolylguanidine (DTG) and haloperidol but not to...

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Bibliographic Details
Main Authors:	Uyen B. Chu, Timur A. Mavlyutov, Ming-Liang Chu, Huan Yang, Amanda Schulman, Christophe Mesangeau, Christopher R. McCurdy, Lian-Wang Guo, Arnold E. Ruoho
Format:	Article
Language:	English
Published:	Elsevier 2015-11-01
Series:	EBioMedicine
Subjects:	Progesterone receptor membrane component-1 (PGRMC1) Sigma-2 receptor (S2R) [3H]-1,3-Di-o-tolylguanidine ([3H]-DTG) [125I]-Iodoazido-fenpropimorph ([125I]-IAF) Clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 knockout***
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396415301808

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http://www.sciencedirect.com/science/article/pii/S2352396415301808

The Sigma-2 Receptor and Progesterone Receptor Membrane Component 1 are Different Binding Sites Derived From Independent Genes

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