Mesenchymal stem cells overexpressing hepatocyte nuclear factor-4 alpha alleviate liver injury by modulating anti-inflammatory functions in mice

Mesenchymal stem cells overexpressing hepatocyte nuclear factor-4 alpha alleviate liver injury by modulating anti-inflammatory functions in mice

Abstract Background Mesenchymal stem cells (MSCs) can migrate to tissue injury sites where they can induce multipotential differentiation and anti-inflammation effects to treat tissue injury. When traditional therapeutic methods do not work, MSCs are considered to be one of the best candidates for c...

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Bibliographic Details
Main Authors: Zhenxiong Ye, Wenfeng Lu, Lei Liang, Min Tang, Yunfeng Wang, Zhen Li, Heping Zeng, Aili Wang, Moubin Lin, Lei Huang, Hui Wang, Hai Hu
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Hepatocyte nuclear factor-4 alpha
Liver injury
Immune regulation
Online Access:http://link.springer.com/article/10.1186/s13287-019-1260-7

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http://link.springer.com/article/10.1186/s13287-019-1260-7

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