Amelioration of neuropilin-1 and RAGE/matrix metalloproteinase-2 pathway-induced renal injury in diabetic rats by rosuvastatin

Amelioration of neuropilin-1 and RAGE/matrix metalloproteinase-2 pathway-induced renal injury in diabetic rats by rosuvastatin

Advanced glycation end-products (AGEs) induce the production of reactive oxygen species (ROS) and extra cellular matrix (ECM) degradation via suppression of neuropilin-1 (NRP-1) and interaction with AGE-receptors (RAGE). This study aimed to reveal whether modulation of NRP-1 by rosuvastatin (RT) pre...

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Bibliographic Details
Main Authors: Nabi Rabia, Alvi Sultan Sahir, Alouffi Sultan, Khan Saif, Ahmad Adnan, Khan Mahvish, Ahmad Saheem, Khan Salman M.
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2021-01-01
Series:Archives of Biological Sciences
Subjects:
rosuvastatin
neuropilin-1
age/rage-signaling
carboxymethyl-lysine
fluorogenic ages
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2021/0354-46642100021N.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0354-4664/2021/0354-46642100021N.pdf

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