Metformin treatment for 8 days impacts multiple intestinal parameters in high-fat high-sucrose fed mice

Abstract Although the mechanism of action of the antidiabetic drug metformin is still a matter of discussions, it is well accepted that the gut plays an important role. To gain more insights into the mechanisms occurring in the different regions of the intestine, adult male mice were fed a high-fat-...

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Bibliographic Details
Main Authors: Amélie Bravard, Céline Gérard, Clémence Defois, Bérengère Benoit, Kassem Makki, Emmanuelle Meugnier, Dominique Rainteau, Jennifer Rieusset, Murielle Godet, Hubert Vidal
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95117-0