Metformin ameliorates maternal high-fat diet-induced maternal dysbiosis and fetal liver apoptosis

Metformin ameliorates maternal high-fat diet-induced maternal dysbiosis and fetal liver apoptosis

Abstract Background The deleterious effect of maternal high-fat diet (HFD) on the fetal rat liver may cause later development of non-alcoholic fatty liver disease (NAFLD). The aim of this study was to evaluate the effect of maternal HFD-induced maternal hepatic steatosis and dysbiosis on the fetal l...

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Main Authors: Szu-Wei Huang, Yu-Che Ou, Kuo-Shu Tang, Hong-Ren Yu, Li-Tung Huang, You-Lin Tain, I-Chun Lin, Jiunn-Ming Sheen, Chih-Yao Hou, Ching-Chou Tsai, Mao-Meng Tiao
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Lipids in Health and Disease
Subjects:
Fatty liver
High-fat diet
Pregnancy
Metformin
Microbiota
Apoptosis
Online Access:https://doi.org/10.1186/s12944-021-01521-w

Internet

https://doi.org/10.1186/s12944-021-01521-w

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