A Bioactive Compound from <i>Sanguisorba officinalis</i> L. Inhibits Cell Proliferation and Induces Cell Death in 5-Fluorouracil-Sensitive/Resistant Colorectal Cancer Cells

A Bioactive Compound from <i>Sanguisorba officinalis</i> L. Inhibits Cell Proliferation and Induces Cell Death in 5-Fluorouracil-Sensitive/Resistant Colorectal Cancer Cells

Colorectal cancer (CRC) is one of the most common cancer in the world. The first line chemotherapeutic agent, 5-fluorouracil (5-FU), plays a predominant role in the clinical treatment of CRC. However, with the wide use of 5-FU, more and more CRC patients have been obtaining drug resistance to 5-FU,...

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Bibliographic Details
Main Authors: Weijia Zhang, Chang Peng, Xue Shen, Yuemei Yuan, Wei Zhang, Chunjuan Yang, Meicun Yao
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
colorectal cancer
AGE
apoptosis
autophagy
Wnt/β-catenin signaling pathway
Online Access:https://www.mdpi.com/1420-3049/26/13/3843

Internet

https://www.mdpi.com/1420-3049/26/13/3843

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