Alpha-Lipoic Acid Downregulates IL-1β and IL-6 by DNA Hypermethylation in SK-N-BE Neuroblastoma Cells

Alpha-lipoic acid (ALA) is a pleiotropic molecule with antioxidant and anti-inflammatory properties, of which the effects are exerted through the modulation of NF-kB. This nuclear factor, in fact, modulates different inflammatory cytokines, including IL-1b and IL-6, in different tissues and cell typ...

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Bibliographic Details
Main Authors: Simona Dinicola, Sara Proietti, Alessandra Cucina, Mariano Bizzarri, Andrea Fuso
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/6/4/74