Modelling the suppression of a malaria vector using a CRISPR-Cas9 gene drive to reduce female fertility

Abstract Background Gene drives based on CRISPR-Cas9 technology are increasingly being considered as tools for reducing the capacity of mosquito populations to transmit malaria, and one of the most promising options is driving endonuclease genes that reduce the fertility of female mosquitoes. In par...

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Bibliographic Details
Main Authors: Ace R. North, Austin Burt, H. Charles J. Godfray
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12915-020-00834-z