Effective inactivated influenza vaccine for the elderly using a single-stranded RNA-based adjuvant

Effective inactivated influenza vaccine for the elderly using a single-stranded RNA-based adjuvant

Abstract There is an unmet need for new influenza vaccine strategies that compensate for impaired vaccine responses in elderly individuals. Here, we evaluated the effectiveness of a single-stranded RNA (ssRNA) as an adjuvant to enhance the efficacy of inactivated influenza vaccine (IIV) in mouse mod...

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Main Authors: Yoo-Jin Bang, So-Hee Hong, Hyo-Jung Park, Hye Won Kwak, Yu-Sun Lee, Jae-Yong Kim, Hyeong-Jun Park, Seo-Hyeon Bae, Hye-Jung Kim, Yun-Hee Kim, Hae Li Ko, Sang-In Park, Hun Kim, Gyeongjoo Park, Man-Seong Park, Jun Chang, Jae-Hwan Nam
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91445-3

Internet

https://doi.org/10.1038/s41598-021-91445-3

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