Alterations in Phosphorylated CREB Expression in Different Brain Regions following Short- and Long-Term Morphine Exposure: Relationship to Food Intake

Background. Activation of the cyclic adenosine monophosphate (cAMP)/phosphorylated CREB (P-CREB) system in different brain regions has been implicated in mediating opioid tolerance and dependence, while alteration of this system in the lateral hypothalamus (LH) has been suggested to have a role in f...

Full description

Bibliographic Details
Main Authors: Xiuhai Ren, Kabirullah Lutfy, Michael Mangubat, Monica G. Ferrini, Martin L. Lee, Yanjun Liu, Theodore C. Friedman
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Journal of Obesity
Online Access:http://dx.doi.org/10.1155/2013/764742