scPred: accurate supervised method for cell-type classification from single-cell RNA-seq data

Abstract Single-cell RNA sequencing has enabled the characterization of highly specific cell types in many tissues, as well as both primary and stem cell-derived cell lines. An important facet of these studies is the ability to identify the transcriptional signatures that define a cell type or state...

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Bibliographic Details
Main Authors: Jose Alquicira-Hernandez, Anuja Sathe, Hanlee P. Ji, Quan Nguyen, Joseph E. Powell
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-019-1862-5