p32 heterozygosity protects against age- and diet-induced obesity by increasing energy expenditure

Abstract Obesity is increasing in prevalence and has become a global public health problem. The main cause of obesity is a perturbation in energy homeostasis, whereby energy intake exceeds energy expenditure. Although mitochondrial dysfunction has been linked to the deregulation of energy homeostasi...

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Bibliographic Details
Main Authors: Yong Liu, Patrick L. Leslie, Aiwen Jin, Koji Itahana, Lee M. Graves, Yanping Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06209-9