In silico drug repositioning using deep learning and comprehensive similarity measures

In silico drug repositioning using deep learning and comprehensive similarity measures

Abstract Background Drug repositioning, meanings finding new uses for existing drugs, which can accelerate the processing of new drugs research and development. Various computational methods have been presented to predict novel drug–disease associations for drug repositioning based on similarity mea...

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Bibliographic Details
Main Authors: Hai-Cheng Yi, Zhu-Hong You, Lei Wang, Xiao-Rui Su, Xi Zhou, Tong-Hai Jiang
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Bioinformatics
Subjects:
Drug repositioning
Drug–disease interaction
Gated recurrent units
Gaussian interaction profile kernel
Machine learning
Online Access:https://doi.org/10.1186/s12859-020-03882-y

Internet

https://doi.org/10.1186/s12859-020-03882-y

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