The interaction of cognitive and brain reserve with frailty in the association with mortality: an observational cohort study

Summary: Background: A higher cognitive reserve and brain reserve could decrease mortality risk, but the interaction of these factors with general age-related loss of physical fitness (eg, frailty) remains unclear with regards to mortality. We investigated the associations of cognitive and brain re...

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Main Authors: Jendé L Zijlmans, MD, Sander Lamballais, MSc, Lies Lahousse, PhD, Meike W Vernooij, ProfPhD, M Kamran Ikram, ProfPhD, M Arfan Ikram, ProfPhD, Annemarie I Luik, PhD
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:The Lancet. Healthy Longevity
Online Access:http://www.sciencedirect.com/science/article/pii/S2666756821000283