Pterostilbene Attenuates Astrocytic Inflammation and Neuronal Oxidative Injury After Ischemia-Reperfusion by Inhibiting NF-κB Phosphorylation

Pterostilbene Attenuates Astrocytic Inflammation and Neuronal Oxidative Injury After Ischemia-Reperfusion by Inhibiting NF-κB Phosphorylation

Astrocyte-mediated inflammation and oxidative stress elicit cerebral ischemia-reperfusion (IR) injury after stroke. Nuclear factor (NF)-κB activates astrocytes and generates pro-inflammatory factors. The purpose of the present study is to elucidate the effect of pterostilbene (PTE, a natural stilben...

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Bibliographic Details
Main Authors: Haixiao Liu, Xun Wu, Jianing Luo, Xiaogang Wang, Hao Guo, Dayun Feng, Lei Zhao, Hao Bai, Mingyang Song, Xunyuan Liu, Wei Guo, Xia Li, Liang Yue, Bodong Wang, Yan Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
cerebral ischemia-reperfusion injury
pterostilbene
nuclear factor-κB
astrocyte
inflammation
oxidative stress
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02408/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.02408/full

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