Botanical preparation HX109 inhibits macrophage-mediated activation of prostate epithelial cells through the CCL4-STAT3 pathway: implication for the mechanism underlying HX109 suppression of prostate hyperplasia

Botanical preparation HX109 inhibits macrophage-mediated activation of prostate epithelial cells through the CCL4-STAT3 pathway: implication for the mechanism underlying HX109 suppression of prostate hyperplasia

Benign prostatic hyperplasia (BPH) is one of the most frequently observed diseases in the elderly male population worldwide. A variety of factors such as aging, hormonal imbalance, chronic inflammation, and oxidative stress play an important role in its pathogenesis. We have previously shown that HX...

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Bibliographic Details
Main Authors: Seonung Lim, Hyun-keun Kim, Wonwoo Lee, Sunyoung Kim
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Heliyon
Subjects:
Cell biology
Cell culture
Botany
Bioactive plant product
Inflammation
Natural product
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020311117

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http://www.sciencedirect.com/science/article/pii/S2405844020311117

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