Gut microbiota from high-risk men who have sex with men drive immune activation in gnotobiotic mice and in vitro HIV infection.

Gut microbiota from high-risk men who have sex with men drive immune activation in gnotobiotic mice and in vitro HIV infection.

Men who have sex with men (MSM) have differences in immune activation and gut microbiome composition compared with men who have sex with women (MSW), even in the absence of HIV infection. Gut microbiome differences associated with HIV itself when controlling for MSM, as assessed by 16S rRNA sequenci...

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Bibliographic Details
Main Authors: Sam X Li, Sharon Sen, Jennifer M Schneider, Ka-Na Xiong, Nichole M Nusbacher, Nancy Moreno-Huizar, Michael Shaffer, Abigail J S Armstrong, Erin Severs, Kristine Kuhn, Charles P Neff, Martin McCarter, Thomas Campbell, Catherine A Lozupone, Brent E Palmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007611

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https://doi.org/10.1371/journal.ppat.1007611

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