Immunoprecipitation and mass spectrometry identify non-cell autonomous Otx2 homeoprotein in the granular and supragranular layers of mouse visual cortex [v1; ref status: indexed, http://f1000r.es/40d]

Immunoprecipitation and mass spectrometry identify non-cell autonomous Otx2 homeoprotein in the granular and supragranular layers of mouse visual cortex [v1; ref status: indexed, http://f1000r.es/40d]

Plasticity in the visual cerebral cortex is regulated by the internalization of Otx2 homeoprotein into parvalbumin neurons in cortical layers II/III and IV. However the Otx2 locus is not active in these neurons and the protein is imported from external sources, including the choroid plexus. Because...

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Bibliographic Details
Main Authors: Namsuk Kim, Dario Acampora, Florent Dingli, Damarys Loew, Antonio Simeone, Alain Prochiantz, Ariel A. Di Nardo
Format: Article
Language:English
Published: F1000 Research Ltd 2014-07-01
Series:F1000Research
Subjects:
Chemical Biology of the Cell
Neuronal Signaling Mechanisms
Protein Chemistry & Proteomics
Online Access:http://f1000research.com/articles/3-178/v1

Internet

http://f1000research.com/articles/3-178/v1

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