Coupling size exclusion chromatography to ultracentrifugation improves detection of exosomal proteins from human plasma by LC-MS

Objectives: Exosomes are small lipid bilayer vesicles that are defined by their endocytic origin and size range of 30–140 nm. They are constantly produced by different cell types, by both healthy and abnormal cells, and can be isolated from almost all body fluids.Little information exists in isolati...

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Bibliographic Details
Main Authors: Sara Alameldin, Victor Costina, Hesham A. Abdel-Baset, Katja Nitschke, Phillip Nuhn, Michael Neumaier, Maren Hedtke
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Practical Laboratory Medicine
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Online Access:http://www.sciencedirect.com/science/article/pii/S235255172100041X