Proton-sensing ovarian cancer G protein-coupled receptor 1 on dendritic cells is required for airway responses in a murine asthma model.

Proton-sensing ovarian cancer G protein-coupled receptor 1 on dendritic cells is required for airway responses in a murine asthma model.

Ovarian cancer G protein-coupled receptor 1 (OGR1) stimulation by extracellular protons causes the activation of G proteins and subsequent cellular functions. However, the physiological and pathophysiological roles of OGR1 in airway responses remain largely unknown. In the present study, we show tha...

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Bibliographic Details
Main Authors: Haruka Aoki, Chihiro Mogi, Takeshi Hisada, Takashi Nakakura, Yosuke Kamide, Isao Ichimonji, Hideaki Tomura, Masayuki Tobo, Koichi Sato, Hiroaki Tsurumaki, Kunio Dobashi, Tetsuya Mori, Akihiro Harada, Masanobu Yamada, Masatomo Mori, Tamotsu Ishizuka, Fumikazu Okajima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3823589?pdf=render

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http://europepmc.org/articles/PMC3823589?pdf=render

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