Viral-based rodent and nonhuman primate models of multiple system atrophy: Fidelity to the human disease

Viral-based rodent and nonhuman primate models of multiple system atrophy: Fidelity to the human disease

Multiple system atrophy (MSA) is a rare and extremely debilitating progressive neurodegenerative disease characterized by variable combinations of parkinsonism, cerebellar ataxia, dysautonomia, and pyramidal dysfunction. MSA is a unique synucleinopathy, in which alpha synuclein-rich aggregates are p...

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Bibliographic Details
Main Authors: David J. Marmion, Angela A. Rutkowski, Diptaman Chatterjee, Benjamin M. Hiller, Milton H. Werner, Erwan Bezard, Deniz Kirik, Thomas McCown, Steven J. Gray, Jeffrey H. Kordower
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Neurobiology of Disease
Subjects:
Multiple system atrophy
Alpha synuclein
Nonhuman primate
Models
Oligodendroglia
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996120304599

Internet

http://www.sciencedirect.com/science/article/pii/S0969996120304599

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