Molecular Mechanisms Contributing to Resistance to Tyrosine Kinase-Targeted Therapy for Non-Small Cell Lung Cancer

Molecular Mechanisms Contributing to Resistance to Tyrosine Kinase-Targeted Therapy for Non-Small Cell Lung Cancer

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One of the most important pathways in non-small cell lung cancer (NSCLC) is the epidermal growth factor receptor (EGFR) pathway. This pathway affects several crucial processes in tumor development and progression, including tumor cell proliferation, apoptosis regulation, angiogenesis, and metastatic...

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Bibliographic Details
Main Authors: Fariz Nurwidya, Akiko Murakami, Fumiyuki Takahashi, Kazuhisa Takahashi
Format: Article
Language:English
Published: China Anti-Cancer Association 2012-03-01
Series:Cancer Biology & Medicine
Subjects:
carcinoma
non-small-cell lung
mutation
drug resistance
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/3/577

Internet

http://www.cancerbiomed.org/index.php/cocr/article/view/3/577

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