Cholangiocyte senescence in primary sclerosing cholangitis is associated with disease severity and prognosis

Cholangiocyte senescence in primary sclerosing cholangitis is associated with disease severity and prognosis

Background & Aims: Primary sclerosing cholangitis (PSC) is a rare cholangiopathy of unknown aetiopathogenesis. The aim of this study was to evaluate cellular senescence (CS) marker expression in cholangiocytes of patients with PSC and their correlation with clinical–pathological features and...

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Bibliographic Details
Main Authors: Nora Cazzagon, Samantha Sarcognato, Annarosa Floreani, Giorgia Corrà, Sara De Martin, Vincenza Guzzardo, Francesco Paolo Russo, Maria Guido
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:JHEP Reports
Subjects:
PSC
p16
p21
Senescent cholangiocytes
Fibrosing cholangiopathy
Prognosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555921000628

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http://www.sciencedirect.com/science/article/pii/S2589555921000628

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